Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 14/20 | 0.59 |
| ▸ | FLT1 | P17948 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL10906041 | 0.83 | AHR (0.87) | AHRFLT1MAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL1747904 | 0.81 | AHR (0.65) | AHRFLT1MEN1ALDH1A1KMT2A | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL10692053 | 0.80 | AHR (0.72) | AHRFLT1LMNATSHR | |
| SCHEMBL3096913 | 0.80 | AHR (0.72) | AHRFLT1LMNATSHR | |
| Toluene SCHEMBL27429243 | 0.78 | ACHE (0.65) | AHRACHELMNATSHRALOX12 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL8939 | 0.77 | AHR (1.00) | AHRFLT1MAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29350382 | 0.77 | AHR (1.00) | AHRFLT1MAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29364019 | 0.77 | AHR (1.00) | AHRFLT1MAPK1 | |
| SCHEMBL14458065 | 0.76 | AHR (0.65) | AHRFLT1MAPT | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL14941758 | 0.76 | AHR (0.56) | AHRFLT1ALOX12ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6547712-B1 | Encapsulation hazarous wastes in sulfur | IKARI-LABORATORY FOR ENVIRONMENTAL SCIENCE CO., LTD. (JP) | 2003-04-15 | — | — | US | disclosed |
| US-6083431-A | HEATING MIXTURE OF ORGANOCHLORINE COMPOUND AND SULFUR | IKARI-LABORATORY FOR ENVIRONMENTAL SCIENCE CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |