SCHEMBL174805

SCHEMBL174805

CC(C)(Cc1ccccc1)CC(C)(C)Nc1cccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.49
KDM4E B2RXH2 3/20 0.41
GSK3B P49841 1/20 0.41
LMNA P02545 2/20 0.41
CYP2D6 P10635 2/20 0.41
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
CYP3A4 P08684 3/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 1/20 0.40
ALOX15 P16050 1/20 0.40
CDC25B P30305 1/20 0.40
ATM Q13315 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
CCR4 P51679 3/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4739865 0.81 CCR4 (0.44) MMP8KDM4ELMNAALDH1A1HPGD
SCHEMBL18351233 0.74 ALDH1A1 (0.47) MMP8KDM4ELMNACYP2D6ALDH1A1
SCHEMBL23742330 0.74 ALDH1A1 (0.53) MMP8KDM4EALDH1A1HPGDCYP3A4
SCHEMBL31303189 0.71 IDO1 (0.55) KDM4ELMNACYP2D6ALDH1A1HPGD
SCHEMBL2622223 0.71 IDO1 (0.55) KDM4ELMNACYP2D6ALDH1A1HPGD
SCHEMBL8769127 0.70 KDM4E (0.44) KDM4ELMNAALDH1A1HPGDCYP3A4
SCHEMBL28276509 0.67 SLC6A2 (0.54) MMP8LMNACYP2D6ALDH1A1CYP3A4
SCHEMBL329187 0.67 KDM4E (0.51) MMP8KDM4EGSK3BCYP2D6ALDH1A1
SCHEMBL30904646 0.67 MMP8 (0.48) MMP8KDM4EGSK3BCYP2D6ALDH1A1
SCHEMBL1572105 0.67 SLC6A2 (0.64) LMNACYP2D6ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9057038-B2 Corrosion inhibiting polyalkylene glycol-based lubricant compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2015-06-16 US claimed
CN-103097505-B Corrosion inhibiting polyalkylene glycol-based lubricant compositions DOW GLOBAL TECHNOLOGIES INC 2015-03-11 CN claimed
US-8722598-B2 Grease composition for bearings with improved heat-resistant acoustic life KYODO YUSHI CO., LTD. (JP) 2014-05-13 US claimed
EP-1981955-B9 IMPROVED HIGH TEMPERATURE LUBRICANT COMPOSITIONS INOLEX INVESTMENT CORP (US) 2013-11-13 EP claimed
EP-2611894-A1 CORROSION INHIBITING POLYALKYLENE GLYCOL-BASED LUBRICANT COMPOSITIONS Dow Global Technologies LLC (US) 2013-07-10 EP claimed
US-20130157909-A1 Corrosion Inhibiting Polyalkylene Glycol-Based Lubricant Compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-20 US claimed
CN-103097505-A Corrosion inhibiting polyalkylene glycol-based lubricant compositions DOW GLOBAL TECHNOLOGIES LLC 2013-05-08 CN claimed
EP-2274408-B1 POLYALKYLENE GLYCOL-BASED WIND TURBINE LUBRICANT COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-10-17 EP claimed
WO-2012030537-A1 CORROSION INHIBITING POLYALKYLENE GLYCOL-BASED LUBRICANT COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-08 WO claimed
CN-102066537-A Polyalkylene glycol-based wind turbine lubricant compositions DOW GLOBAL TECHNOLOGIES INC 2011-05-18 CN claimed
US-20110039739-A1 POLYALKYLENE GLYCOL-BASED WIND TURBINE LUBRICANT COMPOSITIONS GREAVES MARTIN 2011-02-17 US claimed
EP-2274408-A1 POLYALKYLENE GLYCOL-BASED WIND TURBINE LUBRICANT COMPOSITIONS Dow Global Technologies Inc. (US) 2011-01-19 EP claimed
WO-2009134656-A1 POLYALKYLENE GLYCOL-BASED WIND TURBINE LUBRICANT COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-05 WO claimed
US-20080317964-A1 High Temperature Lubricant Compositions and Methods of Making the Same INOLEX INVESTMENT CORPORATION 2008-12-25 US claimed
US-20070179069-A1 High temperature lubricant compositions INOLEX INVESTMENT CORPORATION (US) 2007-08-02 US claimed
WO-2006086752-A1 HIGH TEMPERATURE LUBRICANT COMPOSITIONS AND METHODS OF MAKING THE SAME INOLEX INVESTMENT CORPORATION (US) 2006-08-17 WO claimed
EP-3575387-B1 ENGINE OIL COMPOSITION ADEKA CORP (JP) 2022-01-12 EP disclosed
CN-110168060-B Engine oil composition 株式会社ADEKA 2021-12-31 CN disclosed
US-20070179069-A1 High temperature lubricant compositions INOLEX INVESTMENT CORPORATION (US) 2007-08-02 US disclosed
WO-2006086752-A1 HIGH TEMPERATURE LUBRICANT COMPOSITIONS AND METHODS OF MAKING THE SAME INOLEX INVESTMENT CORPORATION (US) 2006-08-17 WO disclosed