Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | MC5R | P33032 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17481411 | 0.95 | PPARA (0.53) | PPARAMAOBGSK3BBACE1LMNA | |
| SCHEMBL17481418 | 0.90 | IDO1 (0.44) | PPARAMAOBGSK3BBACE1LMNA | |
| SCHEMBL17481535 | 0.86 | MEN1 (0.60) | PPARAMAOBGSK3BBACE1LMNA | |
| SCHEMBL8351299 | 0.77 | CHRM2 (0.71) | LMNAMC4RMC5RMC3RCHRM2 | |
| SCHEMBL17481533 | 0.75 | KMT2A (0.48) | PPARAMAOBGSK3BBACE1LMNA | |
| SCHEMBL17611474 | 0.75 | MAOB (0.59) | PPARAMAOBGSK3BBACE1NPSR1 | |
| SCHEMBL5511238 | 0.75 | MAOB (0.58) | PPARAMAOBGSK3BBACE1IDO1 | |
| SCHEMBL3457379 | 0.75 | MAOB (0.58) | PPARAMAOBGSK3BBACE1IDO1 | |
| SCHEMBL5514364 | 0.75 | MAOB (0.62) | PPARAMAOBGSK3BBACE1MEN1 | |
| SCHEMBL4339666 | 0.74 | MAOB (0.61) | PPARAMAOBGSK3BBACE1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031799-A1 | P62-ZZ CHEMICAL INHIBITOR | ID4PHARMA LLC (US) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031799-A1 | P62-ZZ CHEMICAL INHIBITOR | SQSTM1, CTSZ, BECN1 | PPARA 2769/4885MAOB 3820/4885GSK3B 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.