Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17481533 | 0.90 | KMT2A (0.48) | MEN1KMT2APPARAMAOBGSK3B | |
| SCHEMBL17481411 | 0.88 | PPARA (0.53) | MEN1KMT2APPARAMAOBGSK3B | |
| SCHEMBL17481414 | 0.86 | PPARA (0.51) | MEN1KMT2APPARAMAOBGSK3B | |
| SCHEMBL17481532 | 0.85 | KMT2A (0.55) | MEN1KMT2APPARALMNANPSR1 | |
| SCHEMBL5514364 | 0.82 | MAOB (0.62) | MEN1KMT2APPARAMAOBGSK3B | |
| SCHEMBL5020048 | 0.80 | MAOB (0.61) | PPARAMAOB | |
| SCHEMBL2595400 | 0.78 | ACHE (0.48) | MEN1KMT2ASMN1; SMN2CD274USP28 | |
| SCHEMBL7024898 | 0.77 | MAOB (0.68) | PPARAMAOBGSK3BBACE1LMNA | |
| SCHEMBL17611474 | 0.76 | MAOB (0.59) | PPARAMAOBGSK3BBACE1NPSR1 | |
| SCHEMBL5511238 | 0.76 | MAOB (0.58) | PPARAMAOBGSK3BBACE1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031799-A1 | P62-ZZ CHEMICAL INHIBITOR | ID4PHARMA LLC (US) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031799-A1 | P62-ZZ CHEMICAL INHIBITOR | SQSTM1, CTSZ, BECN1 | MEN1 1167/4885KMT2A 756/4885PPARA 2769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.