Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17481414 | 0.90 | PPARA (0.51) | IDO1AGXTMAOBGSK3BBACE1 | |
| SCHEMBL17481533 | 0.86 | KMT2A (0.48) | IDO1AGXTMAOBGSK3BBACE1 | |
| SCHEMBL17481411 | 0.84 | PPARA (0.53) | IDO1AGXTMAOBGSK3BBACE1 | |
| SCHEMBL18313742 | 0.76 | HTR2C (0.47) | MAOBGSK3BBACE1SMN1; SMN2PPARA | |
| SCHEMBL17481535 | 0.75 | MEN1 (0.60) | MAOBGSK3BBACE1SMN1; SMN2PPARA | |
| SCHEMBL18313743 | 0.72 | ALDH1A1 (0.50) | MAOBBACE1KDM4EACHEBCHE | |
| SCHEMBL14303982 | 0.72 | ACHE (0.52) | IDO1AGXTBACE1MC4RMC5R | |
| SCHEMBL16264603 | 0.72 | BCHE (0.59) | MC4RMC5RMC3RCHRM2BCHE | |
| Hydrochloric Acid SCHEMBL29778348 | 0.71 | BCHE (0.58) | MC4RMC5RMC3RBCHE | |
| SCHEMBL8351299 | 0.70 | CHRM2 (0.71) | MC4RMC5RMC3RKDM4EACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031799-A1 | P62-ZZ CHEMICAL INHIBITOR | ID4PHARMA LLC (US) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031799-A1 | P62-ZZ CHEMICAL INHIBITOR | SQSTM1, CTSZ, BECN1 | IDO1 3845/4885AGXT 3485/4885MAOB 3820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.