Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 10/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16863522 | 0.92 | MLYCD (0.36) | MLYCDTSHRDHODHRXFP1 | |
| SCHEMBL17482156 | 0.92 | DHODH (0.37) | MLYCDDHODH | |
| SCHEMBL18355928 | 0.90 | MLYCD (0.35) | MLYCDDHODHRXFP1 | |
| SCHEMBL23026209 | 0.89 | MLYCD (0.35) | MLYCDDHODHHCRTR1HCRTR2 | |
| SCHEMBL18355932 | 0.88 | MLYCD (0.35) | MLYCDDHODH | |
| SCHEMBL17482159 | 0.86 | MLYCD (0.40) | MLYCDTSHRDHODHNPSR1RXFP1 | |
| SCHEMBL22332436 | 0.86 | TSHR (0.36) | TSHRDHODHNPSR1HCRTR1HCRTR2 | |
| SCHEMBL18354409 | 0.85 | DHODH (0.33) | TSHRDHODHNPSR1RXFP1 | |
| SCHEMBL18354699 | 0.85 | DHODH (0.37) | DHODHNPSR1 | |
| SCHEMBL18354527 | 0.85 | DHODH (0.37) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210051955-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-25 | — | — | US | disclosed |
| US-20200253205-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| US-9975845-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-22 | — | — | US | disclosed |
| US-9975845-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-22 | — | — | US | disclosed |
| US-20180077930-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | US | disclosed |
| US-20180077930-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | US | disclosed |
| US-9839216-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-12 | — | — | US | disclosed |
| US-9839216-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-12 | — | — | US | disclosed |
| US-20170152214-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-01 | — | — | US | disclosed |
| US-20170152214-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-01 | — | — | US | disclosed |
| US-9635853-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-02 | — | — | US | disclosed |
| US-9635853-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-02 | — | — | US | disclosed |
| US-20170000120-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
| US-20170000120-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
| US-20160029624-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | US | disclosed |
| US-20160029624-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152214-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | MLYCD 1777/4885TSHR 3230/4885DHODH 2125/4885 |
| US-20200253205-A1 | INSECTICIDAL COMPOUNDS | ACHE, CYP4X1, ITPR3 | MLYCD 1427/4885TSHR 3400/4885DHODH 3024/4885 |
| US-20180077930-A1 | INSECTICIDAL COMPOUNDS | ACHE, CYP4X1, ITPR3 | MLYCD 1427/4885TSHR 3400/4885DHODH 3024/4885 |
| US-20210051955-A1 | INSECTICIDAL COMPOUNDS | ACHE, CYP4X1, ITPR3 | MLYCD 1427/4885TSHR 3400/4885DHODH 3024/4885 |
| US-20170000120-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | MLYCD 1142/4885TSHR 3588/4885DHODH 3226/4885 |
| US-20160029624-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | MLYCD 1777/4885TSHR 3230/4885DHODH 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.