Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694906 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2RAB9ANPC1HTTMAPT | |
| SCHEMBL19902276 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1HTTMAPT | |
| SCHEMBL3712068 | 0.78 | RAB9A (0.67) | SMN1; SMN2RAB9ANPC1HTTMAPT | |
| SCHEMBL27926814 | 0.76 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9ANPC1HTTMAPT | |
| SCHEMBL17468789 | 0.73 | RAB9A (0.61) | SMN1; SMN2RAB9ANPC1HTTMAPT | |
| SCHEMBL17482180 | 0.70 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1HTTMAPT | |
| SCHEMBL3780684 | 0.70 | HTT (0.61) | SMN1; SMN2RAB9ANPC1HTTMAPT | |
| SCHEMBL31655490 | 0.68 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1HTTMAPT | |
| SCHEMBL3661523 | 0.68 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1HTTMAPT | |
| SCHEMBL17482210 | 0.67 | NPSR1 (0.36) | SMN1; SMN2RAB9ANPC1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902748-B2 | Photoactive energetic materials | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2018-02-27 | — | — | US | disclosed |
| US-20160031767-A1 | PHOTOACTIVE ENERGETIC MATERIALS | TRIAD NATIONAL SECURITY, LLC | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031767-A1 | PHOTOACTIVE ENERGETIC MATERIALS | NOX5, TRPM5, MT-ND5 | SMN1; SMN2 4635/4885RAB9A 4208/4885NPC1 2726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.