Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17476686 | 0.73 | KDM4E (0.48) | ADORA2AADORA3ADORA2BADORA1TDO2 | |
| SCHEMBL17482179 | 0.72 | ADORA2A (0.49) | ADORA2AADORA3ADORA2BADORA1TDO2 | |
| SCHEMBL17482203 | 0.72 | MAPT (0.34) | ADORA2AADORA3ADORA2BADORA1LMNA | |
| SCHEMBL17482197 | 0.70 | MET (0.46) | ADORA2AADORA3ADORA2BADORA1LMNA | |
| SCHEMBL27992065 | 0.67 | ADORA2A (0.47) | ADORA2AADORA3ADORA2BADORA1TDO2 | |
| SCHEMBL17482200 | 0.67 | MAPT (0.38) | LMNAALDH1A1MEN1GAAMAPT | |
| SCHEMBL26098451 | 0.65 | KDM4E (0.41) | ADORA2AADORA3ADORA2BADORA1TDO2 | |
| SCHEMBL17482181 | 0.65 | KDM4E (0.50) | ADORA2AADORA3ADORA2BADORA1TDO2 | |
| SCHEMBL28870957 | 0.65 | HTT (0.62) | ADORA2AADORA3ADORA2BADORA1LMNA | |
| SCHEMBL28661523 | 0.65 | TDO2 (0.40) | ADORA2AADORA3ADORA2BADORA1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174064-B2 | Photoactive energetic materials | TRIAD NATIONAL SECURITY, LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-9902748-B2 | Photoactive energetic materials | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2018-02-27 | — | — | US | disclosed |
| US-9902748-B2 | Photoactive energetic materials | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2018-02-27 | — | — | US | disclosed |
| US-20160031767-A1 | PHOTOACTIVE ENERGETIC MATERIALS | TRIAD NATIONAL SECURITY, LLC | 2016-02-04 | — | — | US | disclosed |
| US-20160031767-A1 | PHOTOACTIVE ENERGETIC MATERIALS | TRIAD NATIONAL SECURITY, LLC | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174064-B2 | Photoactive energetic materials | NOX5, TRPM5, MT-ND5 | ADORA2A 565/4885ADORA3 654/4885ADORA2B 1000/4885 |
| US-20160031767-A1 | PHOTOACTIVE ENERGETIC MATERIALS | NOX5, TRPM5, MT-ND5 | ADORA2A 565/4885ADORA3 654/4885ADORA2B 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.