SCHEMBL17483435

SCHEMBL17483435

c1cncc(-c2nc(-c3cccnc3)nc(-c3cccc(-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccccc6n7-c6cccc(-c7nc(-c8cccnc8)nc(-c8cccnc8)n7)c6)ccc54)c3)n2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.42
CYP11B1 P15538 2/20 0.40
CYP11B2 P19099 2/20 0.40
CYP17A1 P05093 1/20 0.40
CYP19A1 P11511 1/20 0.40
GRM5 P41594 1/20 0.39
CYP1A2 P05177 5/20 0.39
ALDH1A1 P00352 5/20 0.39
CYP3A4 P08684 4/20 0.39
CLK4 Q9HAZ1 4/20 0.39
TSHR P16473 3/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP2C19 P33261 1/20 0.39
GLA P06280 1/20 0.39
USP2 O75604 3/20 0.39
LMNA P02545 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17483381 0.98 MAPT (0.43) MAPTCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL17483374 0.98 MAPT (0.43) MAPTCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL17483382 0.98 MAPT (0.43) MAPTCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL17483309 0.96 MAPT (0.43) MAPTCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL17483328 0.96 MAPT (0.43) MAPTCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL18931880 0.94 MAPT (0.41) MAPTCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL23085191 0.93 MAPT (0.41) MAPTCYP1A2ALDH1A1CYP3A4CLK4
SCHEMBL8739891 0.91 CYP11B2 (0.45) MAPTCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL17483434 0.91 TLR8 (0.41) MAPTCYP11B1CYP11B2CYP19A1GRM5
SCHEMBL17483327 0.90 CYP1A2 (0.44) MAPTCYP11B1CYP11B2CYP17A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3171421-B1 ORGANIC LIGHT-EMITTING ELEMENT UNIV KYUSHU NAT UNIV CORP (JP) 2023-01-25 EP disclosed
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
EP-3706182-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kyushu University National University Corporation (JP) 2020-09-09 EP disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10600983-B2 Organic electroluminescent device comprising delayed fluorescent materials KYULUX, INC. (JP) 2020-03-24 US disclosed
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound KYULUX, INC. (JP) 2020-02-11 US disclosed
EP-2980877-B1 ORGANIC ELECTROLUMINESCENT ELEMENT KYULUX INC (JP) 2017-11-29 EP disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
EP-3171421-A1 ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2017-05-24 EP disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160308145-A1 LIGHT-EMITTING MATERIAL, AND DELAYED FLUORESCENT EMITTER AND ORGANIC LIGHT-EMITTING DEVICE USING SAME KYULUX, INC. (JP) 2016-10-20 US disclosed
US-20160308145-A1 LIGHT-EMITTING MATERIAL, AND DELAYED FLUORESCENT EMITTER AND ORGANIC LIGHT-EMITTING DEVICE USING SAME KYULUX, INC. (JP) 2016-10-20 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
EP-2980877-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Kyushu University, National University Corporation (JP) 2016-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND TERB1, TERT, TCOF1 MAPT 643/4885CYP11B1 3540/4885CYP11B2 3639/4885
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound TERB1, TERT, TCOF1 MAPT 643/4885CYP11B1 3540/4885CYP11B2 3639/4885
US-20160308145-A1 LIGHT-EMITTING MATERIAL, AND DELAYED FLUORESCENT EMITTER AND ORGANIC LIGHT-EMITTING DEVICE USING SAME NR2E3, CRY1, ARL1 MAPT 3177/4885CYP11B1 1477/4885CYP11B2 2029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.