Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.82 |
| ▸ | HPGD | P15428 | 2/20 | 0.82 |
| ▸ | POLB | P06746 | 2/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.82 |
| ▸ | NPC1 | O15118 | 2/20 | 0.82 |
| ▸ | RAB9A | P51151 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.82 |
| ▸ | GMNN | O75496 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | GLA | P06280 | 1/20 | 0.82 |
| ▸ | GAA | P10253 | 1/20 | 0.82 |
| ▸ | APEX1 | P27695 | 1/20 | 0.82 |
| ▸ | BLM | P54132 | 1/20 | 0.82 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.82 |
| ▸ | ATP2A1 | O14983 | 1/20 | 0.82 |
| ▸ | MTOR | P42345 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17381105 | 0.96 | MAPT (0.81) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL82423 | 0.90 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL21981207 | 0.90 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL21981209 | 0.90 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL16491487 | 0.90 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL18762159 | 0.90 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL5690389 | 0.90 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL18762158 | 0.90 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL20897006 | 0.90 | MAPT (0.99) | MAPTHPGDPOLBMAPK1KMT2A | |
| SCHEMBL18080775 | 0.90 | MAPT (0.93) | MAPTHPGDPOLBMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845283-B2 | Methods of producing cancer targeting compounds | INSPYR THERAPEUTICS, INC. (US) | 2017-12-19 | — | — | US | disclosed |
| US-9822064-B2 | Methods of producing cancer treating compounds | INSPYR THERAPEUTICS, INC. (US) | 2017-11-21 | — | — | US | disclosed |
| US-20160347706-A1 | Methods of Producing Cancer Compounds | GENSPERA, INC. (US) | 2016-12-01 | — | — | US | disclosed |
| US-20160347730-A1 | Methods of Producing Cancer Compounds | GENSPERA, INC. (US) | 2016-12-01 | — | — | US | disclosed |
| US-9446141-B2 | Methods of producing cancer compounds | GENSPERA, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-20160030589-A1 | Methods of Producing Cancer Compounds | GENSPERA, INC. (US) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160347706-A1 | Methods of Producing Cancer Compounds | HCCS, MYC, SDHA | MAPT 4605/4885HPGD 119/4885POLB 486/4885 |
| US-20160347730-A1 | Methods of Producing Cancer Compounds | HCCS, MYC, SDHA | MAPT 4605/4885HPGD 119/4885POLB 486/4885 |
| US-20160030589-A1 | Methods of Producing Cancer Compounds | NQO1, CYP21A2, CYP11B2 | MAPT 4540/4885HPGD 20/4885POLB 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.