SCHEMBL17484305

SCHEMBL17484305

C[C@@H]1CN(C2CCN(C)CC2)CCN1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.31
L3MBTL3 Q96JM7 1/20 0.31
BIRC2 Q13490 1/20 0.31
NCF1 P14598 1/20 0.30
KDM1A O60341 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17310197 1.00 ALDH1A1 (0.42) ALDH1A1L3MBTL1L3MBTL3BIRC2NCF1
SCHEMBL15933081 1.00 ALDH1A1 (0.42) ALDH1A1L3MBTL1L3MBTL3BIRC2NCF1
SCHEMBL25698895 0.87 BIRC2 (0.34) BIRC2
SCHEMBL23139621 0.87 BIRC2 (0.34) BIRC2
Hydrochloric Acid SCHEMBL25337896 0.85 HPGD (0.34) ALDH1A1BIRC2
Hydrochloric Acid SCHEMBL25337894 0.85 HPGD (0.34) ALDH1A1BIRC2
SCHEMBL18379008 0.84 ALDH1A1 (0.35) ALDH1A1L3MBTL1L3MBTL3NCF1
SCHEMBL14856418 0.83 HTR6 (0.36) ALDH1A1BIRC2
SCHEMBL12350484 0.83 HTR6 (0.36) ALDH1A1BIRC2
SCHEMBL6582291 0.82 HTR6 (0.39) BIRC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3640248-B1 AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) 2023-08-23 EP disclosed
US-20170008888-A1 HETEROCYCLIC COMPOUNDS ACTIVX BIOSCIENCES, INC. 2017-01-12 US disclosed
WO-2016015597-A1 COMPOUNDS AS CDK SMALL-MOLECULE INHIBITORS AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2016-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008888-A1 HETEROCYCLIC COMPOUNDS BET1, EP300, RBBP5 ALDH1A1 3922/4885L3MBTL1 2394/4885L3MBTL3 3050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.