Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174245 | 0.80 | SLC34A1 (0.41) | SLC6A2SLC6A3SLC6A4P2RX7NPBWR1 | |
| SCHEMBL17242886 | 0.77 | NPC1 (0.38) | SLC6A2SLC6A3SLC6A4P2RX7MAPT | |
| SCHEMBL17242974 | 0.77 | CASP3 (0.35) | SLC6A2SLC6A3SLC6A4P2RX7MAPT | |
| SCHEMBL174528 | 0.75 | CRHR1 (0.42) | SLC6A2SLC6A3SLC6A4P2RX7NPBWR1 | |
| SCHEMBL174656 | 0.74 | AR (0.46) | SLC6A2SLC6A3SLC6A4P2RX7HSD11B1 | |
| SCHEMBL176300 | 0.74 | AR (0.46) | SLC6A2SLC6A3SLC6A4P2RX7HSD11B1 | |
| SCHEMBL175108 | 0.73 | SLC6A2 (0.45) | SLC6A2SLC6A3SLC6A4MAPTLMNA | |
| SCHEMBL171101 | 0.73 | HSD11B1 (0.47) | P2RX7LMNAALDH1A1HSD11B1CYP3A4 | |
| SCHEMBL28131183 | 0.73 | SLC6A2 (0.42) | SLC6A2SLC6A3SLC6A4P2RX7MAPT | |
| SCHEMBL877302 | 0.72 | KDM4E (0.58) | P2RX7MAPTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3140289-A1 | FUNGICIDAL PYRAZOLES | E. I. du Pont de Nemours and Company (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20170037014-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2017-02-09 | — | — | US | disclosed |
| WO-2015171392-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-11-12 | — | — | WO | disclosed |
| US-9131693-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2611297-B1 | FUNGICIDAL PYRAZOLES | DU PONT (US) | 2015-06-17 | — | — | EP | disclosed |
| US-20140221448-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-07 | — | — | US | disclosed |
| US-8754115-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-06-17 | — | — | US | disclosed |
| EP-2611297-A1 | FUNGICIDAL PYRAZOLES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130143940-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-06 | — | — | US | disclosed |
| WO-2012030922-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221448-A1 | FUNGICIDAL PYRAZOLES | CYP1A1, CYP1B1, CYP4X1 | SLC6A2 4338/4885SLC6A3 3665/4885SLC6A4 3878/4885 |
| US-20170037014-A1 | FUNGICIDAL PYRAZOLES | CYP1A1, CYP1B1, NOX3 | SLC6A2 4181/4885SLC6A3 3044/4885SLC6A4 3883/4885 |
| US-20130143940-A1 | FUNGICIDAL PYRAZOLES | CYP1A1, CYP1B1, CYP4X1 | SLC6A2 4338/4885SLC6A3 3665/4885SLC6A4 3878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.