Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RAC2 | P15153 | 1/20 | 0.30 |
| ▸ | RAC3 | P60763 | 1/20 | 0.30 |
| ▸ | CDC42 | P60953 | 1/20 | 0.30 |
| ▸ | RAC1 | P63000 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19295156 | 0.94 | PTGER4 (0.34) | KDM4EATML3MBTL1RAC2RAC3 | |
| SCHEMBL19295138 | 0.88 | KDM4E (0.35) | KDM4EATML3MBTL1RXRARAC2 | |
| SCHEMBL17486075 | 0.84 | PTGER4 (0.36) | KDM4EATML3MBTL1RAC2RAC3 | |
| SCHEMBL17485989 | 0.82 | PTGER4 (0.35) | KDM4EATML3MBTL1RAC2RAC3 | |
| SCHEMBL17486070 | 0.81 | HSD17B1 (0.33) | KDM4E | |
| SCHEMBL19508098 | 0.79 | KDM4E (0.43) | KDM4EATML3MBTL1RAC2RAC3 | |
| SCHEMBL17485977 | 0.78 | HSD17B1 (0.34) | KDM4E | |
| SCHEMBL21975093 | 0.77 | L3MBTL1 (0.41) | KDM4EATML3MBTL1RXRARAC2 | |
| SCHEMBL24686231 | 0.76 | TUBB4A (0.42) | KDM4EATML3MBTL1 | |
| SCHEMBL19508096 | 0.76 | KDM4E (0.40) | KDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174890-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-03-13 | — | — | EP | disclosed |
| US-9853228-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-26 | — | — | US | disclosed |
| US-9853228-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-26 | — | — | US | disclosed |
| US-20170250353-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-08-31 | — | — | US | disclosed |
| US-20170250353-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-08-31 | — | — | US | disclosed |
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170250353-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | KDM4E 3816/4885ATM 3760/4885L3MBTL1 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.