Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 12/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17485999 | 0.79 | KDM4E (0.34) | KDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL17486134 | 0.78 | TDP1 (0.35) | KDM4EALDH1A1TDP1L3MBTL1HPGD | |
| SCHEMBL17486165 | 0.75 | CYP11B2 (0.35) | CTSSCTSKALDH1A1L3MBTL1 | |
| SCHEMBL17486289 | 0.74 | NOTUM (0.33) | — | |
| SCHEMBL17486186 | 0.71 | CYP11B1 (0.31) | KDM4EALDH1A1 | |
| SCHEMBL19295094 | 0.69 | LIPE (0.32) | — | |
| SCHEMBL17486083 | 0.68 | HSD17B1 (0.33) | CTSKKDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL17486175 | 0.68 | — | — | |
| SCHEMBL19295157 | 0.66 | NPC1 (0.36) | ALDH1A1 | |
| SCHEMBL17485980 | 0.66 | HSD17B1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174890-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-03-13 | — | — | EP | disclosed |
| US-9853228-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-26 | — | — | US | disclosed |
| US-20170250353-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-08-31 | — | — | US | disclosed |
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170250353-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | CTSS 1272/4885AR 3913/4885CTSK 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.