Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486238 | 0.88 | ALOX5 (0.39) | ALOX5L3MBTL1BACE1BACE2PARP14 | |
| SCHEMBL17485966 | 0.83 | ALOX5 (0.36) | ALOX5L3MBTL1BACE1BACE2PARP14 | |
| SCHEMBL17486348 | 0.81 | MEN1 (0.35) | L3MBTL1ALOX5APFEN1 | |
| SCHEMBL17486349 | 0.77 | KDM4E (0.37) | — | |
| SCHEMBL17486208 | 0.77 | MEN1 (0.34) | — | |
| SCHEMBL17486350 | 0.76 | CYP2A6 (0.39) | — | |
| SCHEMBL17486353 | 0.75 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL17486354 | 0.74 | CYP1A2 (0.41) | ALOX5APFEN1 | |
| SCHEMBL17486352 | 0.73 | DGAT1 (0.32) | — | |
| SCHEMBL17486234 | 0.72 | S1PR1 (0.37) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |