Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486348 | 0.83 | MEN1 (0.35) | SMN1; SMN2KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL17486354 | 0.82 | CYP1A2 (0.41) | CYP1A2NPC1CA12CA1CA2 | |
| SCHEMBL17486352 | 0.81 | DGAT1 (0.32) | MAPTDGAT1 | |
| SCHEMBL17486349 | 0.77 | KDM4E (0.37) | SMN1; SMN2TP53KDM4EMAPTALDH1A1 | |
| SCHEMBL17486208 | 0.77 | MEN1 (0.34) | SMN1; SMN2KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL17486350 | 0.77 | CYP2A6 (0.39) | SMN1; SMN2TP53MAPTCYP2C19NPC1 | |
| SCHEMBL17486197 | 0.75 | ALOX5 (0.36) | — | |
| SCHEMBL17486257 | 0.74 | DGAT1 (0.35) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17485987 | 0.73 | — | — | |
| SCHEMBL17486202 | 0.72 | RARG (0.35) | SMN1; SMN2KDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |