Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 9/20 | 0.38 |
| ▸ | RARB | P10826 | 9/20 | 0.38 |
| ▸ | RARG | P13631 | 10/20 | 0.37 |
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486303 | 0.91 | L3MBTL1 (0.46) | RARARARBRARGRXRAHSD17B1 | |
| SCHEMBL17486299 | 0.85 | RARB (0.37) | RARARARBRARGRXRAHSD17B1 | |
| SCHEMBL17486329 | 0.85 | RARB (0.42) | RARARARBRARGRXRAHSD17B1 | |
| SCHEMBL17486029 | 0.84 | RARB (0.44) | RARARARBRARGRXRAHSD17B1 | |
| SCHEMBL17486298 | 0.83 | RARA (0.36) | RARARARBRARGRXRAHSD17B1 | |
| SCHEMBL17485986 | 0.83 | RARA (0.36) | RARARARBRARGRXRAHSD17B1 | |
| SCHEMBL17486034 | 0.82 | HSD17B1 (0.36) | RARGHSD17B1HSD17B2BACE1L3MBTL1 | |
| SCHEMBL17486338 | 0.82 | NPC1 (0.39) | RARARARBRARGRXRAL3MBTL1 | |
| SCHEMBL18015622 | 0.81 | KDM1A (0.38) | RARARARBRARGRXRABACE1 | |
| SCHEMBL17486333 | 0.81 | RARB (0.47) | RARARARBRARGRXRAHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174890-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-03-13 | — | — | EP | disclosed |
| US-9853228-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-26 | — | — | US | disclosed |
| US-9853228-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-26 | — | — | US | disclosed |
| US-20170250353-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-08-31 | — | — | US | disclosed |
| US-20170250353-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-08-31 | — | — | US | disclosed |
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170250353-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | RARA 3284/4885RARB 3717/4885RARG 3452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.