Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15977624 | 0.88 | L3MBTL1 (0.48) | OPRM1ADAM17KMT2AALDH1A1MEN1 | |
| SCHEMBL15978574 | 0.87 | OPRM1 (0.41) | OPRM1ADAM17KMT2AALDH1A1MEN1 | |
| SCHEMBL17489528 | 0.83 | SLC6A2 (0.47) | — | |
| SCHEMBL23020811 | 0.80 | OPRM1 (0.43) | OPRM1KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL11076991 | 0.77 | OPRM1 (0.50) | OPRM1ADAM17KMT2AMEN1HTT | |
| SCHEMBL11076988 | 0.77 | OPRM1 (0.50) | OPRM1ADAM17KMT2AMEN1HTT | |
| SCHEMBL15978559 | 0.76 | ADAM17 (0.57) | OPRM1ADAM17ALDH1A1HTTL3MBTL1 | |
| SCHEMBL19585730 | 0.76 | ADAM17 (0.57) | OPRM1ADAM17ALDH1A1HTTL3MBTL1 | |
| SCHEMBL11074900 | 0.75 | ADAM17 (0.54) | ADAM17KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL17792929 | 0.75 | ALDH1A1 (0.47) | OPRM1ADAM17KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160032330-A1 | P-450-CATALYZED ENANTIOSELECTIVE CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-02-04 | — | — | US | disclosed |