Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17487771 | 0.91 | P2RX3 (0.42) | P2RX3 | |
| SCHEMBL17488005 | 0.89 | CYP3A4 (0.41) | P2RX3CYP3A4 | |
| SCHEMBL17488307 | 0.86 | CYP3A4 (0.41) | P2RX3CYP3A4 | |
| SCHEMBL17488296 | 0.85 | P2RX3 (0.41) | P2RX3 | |
| SCHEMBL17488212 | 0.84 | CYP3A4 (0.41) | P2RX3CYP3A4 | |
| SCHEMBL17487731 | 0.84 | P2RX3 (0.41) | P2RX3CYP3A4 | |
| SCHEMBL17488173 | 0.84 | CYP3A4 (0.48) | P2RX3CYP3A4 | |
| SCHEMBL18965845 | 0.83 | CYP3A4 (0.41) | P2RX3CYP3A4 | |
| SCHEMBL17487446 | 0.83 | CYP3A4 (0.47) | P2RX3CYP3A4 | |
| SCHEMBL17488306 | 0.83 | CYP3A4 (0.40) | P2RX3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166563-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2017-06-15 | — | — | US | disclosed |
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166563-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | ALOX5, ALOX15, ALOX12 | P2RX3 750/4885CYP3A4 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.