Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.32 |
| ▸ | PDE9A | O76083 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | VNN1 | O95497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488336 | 0.91 | SCN9A (0.42) | SCN9A | |
| SCHEMBL17488339 | 0.82 | GRM4 (0.36) | FABP4PIM1 | |
| SCHEMBL18965793 | 0.82 | MAPT (0.37) | PDPK1CACNA1BSCN9ACACNA1HMCHR1 | |
| SCHEMBL17488236 | 0.79 | RAB9A (0.42) | CACNA1BCACNA1HMCHR1 | |
| SCHEMBL17488043 | 0.78 | RAB9A (0.39) | MCHR1 | |
| SCHEMBL17488103 | 0.77 | SCN9A (0.47) | SCN9AMCHR1 | |
| SCHEMBL17488096 | 0.76 | RAB9A (0.42) | — | |
| SCHEMBL17487492 | 0.74 | CSNK1A1 (0.41) | CACNA1BCACNA1H | |
| SCHEMBL17487488 | 0.74 | RAB9A (0.41) | FABP4SCN9AMCHR1 | |
| SCHEMBL17488131 | 0.73 | MCHR1 (0.41) | CACNA1BSCN9ACACNA1HMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |