Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 15/20 | 0.42 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488334 | 0.91 | FABP4 (0.34) | SCN9A | |
| SCHEMBL17488339 | 0.89 | GRM4 (0.36) | — | |
| SCHEMBL17488103 | 0.87 | SCN9A (0.47) | SCN9ASCN7AKCNH2SCN5ABRD4 | |
| SCHEMBL18965997 | 0.82 | SCN9A (0.42) | SCN9ASCN7AKCNH2SCN5ALIPE | |
| SCHEMBL17488159 | 0.78 | RAB9A (0.41) | SCN9AKDRTEKLMNA | |
| SCHEMBL17488240 | 0.75 | RAB9A (0.41) | SCN9AKDRTEKLMNA | |
| SCHEMBL17488105 | 0.75 | RAB9A (0.41) | KCNH2LMNA | |
| SCHEMBL17488253 | 0.74 | SCN9A (0.46) | SCN9ASCN7AKCNH2SCN5A | |
| SCHEMBL17488013 | 0.73 | RAB9A (0.39) | KCNH2KDRLMNA | |
| SCHEMBL17487676 | 0.73 | CYP3A4 (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |