Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30629173 | 1.00 | CYP2B6 (0.42) | CYP2B6CYP1A1CYP1A2ALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL6245847 | 0.98 | CYP2B6 (0.41) | CYP2B6CYP1A1CYP1A2ALDH1A1ALOX15 | |
| Propionic Acid SCHEMBL28248103 | 0.91 | CYP2B6 (0.37) | CYP2B6CYP1A1CYP1A2ALDH1A1ALOX15 | |
| SCHEMBL7531329 | 0.89 | ALDH1A1 (0.35) | CYP2B6CYP1A1CYP1A2ALDH1A1ALOX15 | |
| SCHEMBL30066970 | 0.85 | PARP1 (0.50) | CYP2B6CYP1A1CYP1A2ALDH1A1ALOX15 | |
| SCHEMBL5322267 | 0.85 | PARP1 (0.50) | CYP2B6CYP1A1CYP1A2ALDH1A1ALOX15 | |
| SCHEMBL7416857 | 0.81 | PARP1 (0.36) | ALDH1A1ALOX15KDM4ETSHRNR4A1 | |
| SCHEMBL31058480 | 0.81 | CYP2B6 (0.39) | CYP2B6CYP1A1CYP1A2ALDH1A1KDM4E | |
| SCHEMBL27383030 | 0.81 | TRPA1 (0.46) | CYP2B6ALDH1A1KDM4ETSHRTDP1 | |
| Succinic Acid SCHEMBL5320883 | 0.81 | PARP1 (0.43) | CYP2B6CYP1A1CYP1A2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528147-B2 | Pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors | AVENTIS PHARMA S.A. (FR) | 2009-05-05 | — | — | US | claimed |
| US-20070093480-A1 | Novel pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors | AVENTIS PHARMA S.A. (FR) | 2007-04-26 | — | — | US | claimed |
| CN-1257489-A | Substituted benzopyran derivatives for the treatment of inflammation | SEARLE & CO (US) | 2000-06-21 | — | — | CN | claimed |
| WO-2025042896-A1 | DNA TOPOISOMERASE IIβ INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2025-02-27 | — | — | WO | disclosed |
| CN-118108725-A | Chiral aza-bridged ring compound, and preparation method and application thereof | 四川大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-117015530-A | Urolithin derivatives and methods of use thereof | 范徳利亚股份公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-114957239-B | Chiral fluorine-containing tropane derivative and preparation method and application thereof | 四川大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-108164495-B | A kind of water solubility coumarin sulfonic acid sodium of benzo containing carboxy hydroxy and preparation method and application | 陕西师范大学 | 2019-10-25 | — | — | CN | disclosed |
| CN-109020961-A | Antiviral compound | 吉利德制药有限责任公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-104230900-B | Antiviral compound | 吉利德制药有限责任公司 | 2018-10-19 | — | — | CN | disclosed |
| CN-108164495-A | A kind of water solubility coumarin sulfonic acid sodium of benzo containing carboxy hydroxy and preparation method and application | 陕西师范大学 | 2018-06-15 | — | — | CN | disclosed |
| CN-1768050-A | Benzopyran compounds for the treatment of inflammation | PHARMACIA CORP (US) | 2006-05-03 | — | — | CN | disclosed |
| EP-1546086-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-29 | — | — | EP | disclosed |
| CN-1196692-C | Substituted benzopyran derivatives for the treatment of inflammation | SEARLE & CO (US) | 2005-04-13 | — | — | CN | disclosed |
| CN-1515566-A | Substituted chromene derivative for curing inflammation | G.D. | 2004-07-28 | — | — | CN | disclosed |
| WO-2004002939-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-08 | — | — | WO | disclosed |
| CN-1257489-A | Substituted benzopyran derivatives for the treatment of inflammation | SEARLE & CO (US) | 2000-06-21 | — | — | CN | disclosed |
| CN-1052006-C | Dihydrobenzopyran derivatives as vasoconstrictors, preparation and use thereof | JANSSEN PHARMACEUTICA NV (NL) | 2000-05-03 | — | — | CN | disclosed |
| US-5824682-A | Vasoconstrictive dihydrobenzopyran derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 1998-10-20 | — | — | US | disclosed |
| CN-1129451-A | Dihydrobenzopyran derivatives as vasoconstrictors | JANSSEN PHARMACEUTICA NV (BE) | 1996-08-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093480-A1 | Novel pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors | MAP3K19, MAP4K2, MAP3K1 | CYP2B6 1518/4885CYP1A1 1915/4885CYP1A2 1546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.