SCHEMBL17488993

SCHEMBL17488993

Cc1cccc(C)c1N(CCC(=O)O)CCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 2/20 0.42
ITGAV P06756 2/20 0.42
ITGB1 P05556 1/20 0.41
ITGA5 P08648 1/20 0.41
FFAR1 O14842 3/20 0.41
APEX1 P27695 1/20 0.41
TSHR P16473 1/20 0.40
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
PTGS2 P35354 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
P2RX7 Q99572 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
EGFR P00533 1/20 0.38
HDAC6 Q9UBN7 2/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14557256 0.89 HDAC3 (0.40) ITGB3ITGAVFFAR1TSHRMAPT
SCHEMBL11220075 0.80 ITGB3 (0.40) ITGB3ITGAVITGB1ITGA5FFAR1
SCHEMBL341369 0.80 TDP1 (0.41) ITGB3ITGAVITGB1ITGA5TSHR
SCHEMBL11141812 0.77 ESR1 (0.40) ITGB3ITGAVITGB1ITGA5TSHR
SCHEMBL9831398 0.76 SMN1; SMN2 (0.47) MAPTSMN1; SMN2ALDH1A1CYP3A4POLB
SCHEMBL11435633 0.76 ALDH1A1 (0.44) ITGB3ITGAVITGB1ITGA5TSHR
SCHEMBL13603849 0.74 KMT2A (0.39) ITGB3ITGAVITGB1ITGA5TSHR
SCHEMBL11138800 0.74 ELANE (0.41) MAPTKDM4EMEN1GAAKMT2A
SCHEMBL27508738 0.73 S1PR4 (0.41) ITGB3ITGAVTSHRMAPTKDM4E
SCHEMBL2808504 0.73 RAB9A (0.46) FFAR1MAPTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9826129-B2 Near-infrared-ray-absorbing composition, near-infrared-ray cut filter using same, manufacturing method therefor, camera module, and manufacturing method therefor FUJIFILM CORPORATION (JP) 2017-11-21 US disclosed
US-9826129-B2 Near-infrared-ray-absorbing composition, near-infrared-ray cut filter using same, manufacturing method therefor, camera module, and manufacturing method therefor FUJIFILM CORPORATION (JP) 2017-11-21 US disclosed
US-20160037034-A1 NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-02-04 US disclosed
US-20160037034-A1 NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160037034-A1 NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR FAR1, SLC39A11, NOTUM ITGB3 4545/4885ITGAV 1499/4885ITGB1 3060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.