SCHEMBL17491464

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17491381	0.87	NPC1 (0.57)	NPC1KDM4EPKMRAB9AALDH1A1
	SCHEMBL17491446	0.82	KDM4E (0.51)	NPC1KDM4EPKMRAB9AALDH1A1
	SCHEMBL17491475	0.82	P2RX1 (0.51)	NPC1KDM4EPKMRAB9AALDH1A1
	SCHEMBL17491421	0.81	KDM4E (0.50)	NPC1KDM4EPKMRAB9AALDH1A1
	SCHEMBL17491479	0.78	PGR (0.59)	PKMLMNAKMT2APOLB
	SCHEMBL19077869	0.78	GRM5 (0.61)	NPC1RAB9AKCNQ3KCNQ2KCNE1
	SCHEMBL12218356	0.75	RAB9A (0.73)	NPC1KDM4ERAB9ALMNAKCNQ3
	SCHEMBL17491492	0.71	ROCK2 (0.46)	NPC1KDM4EPKMRAB9AALDH1A1
	SCHEMBL16775716	0.70	LMNA (0.48)	PKMLMNAMEN1KMT2A
	SCHEMBL13702109	0.69	ERN1 (0.49)	NPC1KDM4EPKMRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.