Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 17/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OXGR1 | Q96P68 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265814 | 0.77 | SUCNR1 (0.53) | SUCNR1KDM4EOXGR1BDKRB1 | |
| SCHEMBL6563211 | 0.77 | SUCNR1 (0.61) | SUCNR1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL11036318 | 0.77 | LMNA (0.58) | LMNAMEN1KMT2A | |
| SCHEMBL24194292 | 0.76 | SUCNR1 (0.49) | SUCNR1LMNAKDM4EOXGR1BDKRB1 | |
| SCHEMBL276117 | 0.76 | SUCNR1 (0.50) | SUCNR1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL6899530 | 0.76 | SUCNR1 (0.47) | SUCNR1OXGR1PDE10A | |
| SCHEMBL30471836 | 0.76 | SUCNR1 (0.57) | SUCNR1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL24193793 | 0.76 | SUCNR1 (0.57) | SUCNR1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL21314499 | 0.75 | TDP1 (0.48) | SUCNR1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL30487489 | 0.75 | TDP1 (0.48) | SUCNR1LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246132-A1 | FLUORINATED 3-(2-OXO-3-(3-ARYLPROPYL)IMIDAZOLIDIN-1-YL)-3-ARYLPROPANOIC ACID DERIVATIVES | OCUTERRA THERAPEUTICS, INC. | 2021-08-12 | — | — | US | disclosed |
| US-10155758-B2 | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2018-12-18 | — | — | US | disclosed |
| US-20180016276-A1 | FLUORINATED 3-(2-OXO-3-(3-ARYLPROPYL)IMIDAZOLIDIN-1-YL)-3-ARYLPROPANOIC ACID DERIVATIVES | FELIQS CORPORATION (JP) | 2018-01-18 | — | — | US | disclosed |
| US-9802933-B2 | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-9266884-B2 | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-y1)-3-arylpropanoic acid derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2016-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016276-A1 | FLUORINATED 3-(2-OXO-3-(3-ARYLPROPYL)IMIDAZOLIDIN-1-YL)-3-ARYLPROPANOIC ACID DERIVATIVES | ITGB3, ITGA2, ITGA1 | SUCNR1 825/4885LMNA 2972/4885KDM4E 4092/4885 |
| US-10155758-B2 | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives | ITGB3, ITGA2, ITGA1 | SUCNR1 825/4885LMNA 2972/4885KDM4E 4092/4885 |
| US-20210246132-A1 | FLUORINATED 3-(2-OXO-3-(3-ARYLPROPYL)IMIDAZOLIDIN-1-YL)-3-ARYLPROPANOIC ACID DERIVATIVES | ITGB3, ITGA2, ITGA1 | SUCNR1 825/4885LMNA 2972/4885KDM4E 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.