Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6518333 | 1.00 | MMP1 (0.37) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL8055747 | 1.00 | MMP1 (0.37) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL3279679 | 0.80 | MMP1 (0.41) | MMP1MMP2MMP3MMP9KMT2A | |
| SCHEMBL6448028 | 0.79 | MMP1 (0.37) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL6265353 | 0.75 | ALDH1A1 (0.35) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL2634811 | 0.75 | ALDH1A1 (0.35) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL9451088 | 0.75 | ALDH1A1 (0.35) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL3285121 | 0.75 | EPHX1 (0.54) | THRBFNTAFNTBPGGT1BFAAH | |
| SCHEMBL23343471 | 0.74 | — | — | |
| SCHEMBL3277705 | 0.73 | EPHX1 (0.57) | THRBFNTAFNTBPGGT1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768502-A1 | INK COMPOSITION FOR COSMETIC CONTACT LENSES | Johnson & Johnson Vision Care, Inc. (US) | 2021-01-27 | — | — | EP | claimed |
| WO-2019180591-A1 | INK COMPOSITION FOR COSMETIC CONTACT LENSES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2019-09-26 | — | — | WO | claimed |
| WO-2016025747-A1 | NONLINEAR COPOLYMERS AS INTRACELLULAR DELIVERY VEHICLES AND RELATED METHODS | STAYTON PATRICK S (US) | 2016-02-18 | — | — | WO | disclosed |