Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16101645 | 0.85 | ALDH1A1 (0.43) | TSHRNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL17499229 | 0.84 | TSHR (0.41) | TSHRNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL17499641 | 0.83 | RAB9A (0.38) | TSHRNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL17499223 | 0.78 | ALDH1A1 (0.30) | RAB9ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL17499126 | 0.78 | KDM4E (0.50) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17499544 | 0.77 | ALDH1A1 (0.32) | ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL17499692 | 0.77 | TDP1 (0.32) | ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL17499296 | 0.77 | ATM (0.38) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17499663 | 0.76 | ALDH1A1 (0.32) | ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL17499253 | 0.75 | NAMPT (0.34) | TSHRRAB9AKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |