Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102952 | 0.86 | ALDH1A1 (0.42) | SMN1; SMN2LMNAALDH1A1L3MBTL1CYP2D6 | |
| SCHEMBL17499743 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAALDH1A1L3MBTL1CYP2D6 | |
| SCHEMBL17499253 | 0.84 | NAMPT (0.34) | SMN1; SMN2LMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL17499671 | 0.80 | TBXA2R (0.39) | SMN1; SMN2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL17499237 | 0.78 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1CYP2D6KMT2AMEN1 | |
| SCHEMBL16101812 | 0.78 | ESR1 (0.30) | — | |
| SCHEMBL16100921 | 0.78 | ESR1 (0.30) | — | |
| SCHEMBL17499239 | 0.78 | RAB9A (0.46) | SMN1; SMN2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL17499229 | 0.77 | TSHR (0.41) | SMN1; SMN2ALDH1A1KMT2ATP53MEN1 | |
| SCHEMBL16098690 | 0.77 | GAA (0.31) | SMN1; SMN2LMNATP53GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |