Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499598 | 0.86 | LMNA (0.43) | DRD2HTR1ALMNAGAAPKM | |
| SCHEMBL17499494 | 0.86 | — | — | |
| SCHEMBL17499156 | 0.85 | CYP19A1 (0.32) | CYP1A2CYP2D6ALDH1A1POLB | |
| SCHEMBL17499203 | 0.83 | CHRNA7 (0.36) | DRD2HTR1ACHRNB2CHRNA4LMNA | |
| SCHEMBL17499338 | 0.81 | KDM4E (0.32) | NOTUMCYP1A2POLB | |
| SCHEMBL17499540 | 0.78 | MEN1 (0.32) | ALDH1A1 | |
| SCHEMBL17499619 | 0.77 | — | — | |
| SCHEMBL17499429 | 0.77 | KDM1A (0.34) | GAAPKML3MBTL1ALDH1A1 | |
| SCHEMBL17499644 | 0.77 | ALDH1A1 (0.47) | LMNAGAACYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL17499647 | 0.77 | ALDH1A1 (0.47) | LMNAGAACYP1A2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |