Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499653 | 0.85 | ADRA2A (0.33) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL17499330 | 0.85 | ALDH1A1 (0.46) | KMT2AMEN1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL17499656 | 0.84 | MEN1 (0.36) | KMT2AMEN1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL17499485 | 0.83 | KMT2A (0.36) | KMT2AMEN1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL17499467 | 0.82 | POLB (0.38) | KMT2AMEN1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL17499126 | 0.81 | KDM4E (0.50) | KMT2AMEN1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL17499490 | 0.81 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTHSD17B10RAB9A | |
| SCHEMBL17499293 | 0.81 | GRM5 (0.37) | ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL17499449 | 0.80 | HSP90AA1 (0.40) | ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL17499101 | 0.79 | POLB (0.36) | KMT2AMEN1TDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |