Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499331 | 0.85 | KMT2A (0.36) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL17499645 | 0.85 | ALDH1A1 (0.32) | MAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL17499435 | 0.85 | ALDH1A1 (0.34) | ADRA2AADRA2BADRA2CPLAUMAPT | |
| SCHEMBL17499298 | 0.85 | ALDH1A1 (0.44) | MAPTNPC1RAB9AKMT2ATP53 | |
| SCHEMBL17499699 | 0.82 | ADRA2A (0.33) | ADRA2AADRA2BADRA2CPLAUMAPT | |
| SCHEMBL17499126 | 0.82 | KDM4E (0.50) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL17499219 | 0.82 | HKDC1 (0.36) | PLAUMAPTNPC1RAB9AKMT2A | |
| SCHEMBL17499449 | 0.81 | HSP90AA1 (0.40) | MAPTALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL17499467 | 0.80 | POLB (0.38) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL17499612 | 0.80 | GRIN1 (0.32) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |