Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499640 | 0.85 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTHSD17B10KDM4E | |
| SCHEMBL17499149 | 0.83 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTHSD17B10KDM4E | |
| SCHEMBL17499219 | 0.82 | HKDC1 (0.36) | ALDH1A1LMNAMAPTHSD17B10KDM4E | |
| SCHEMBL17499504 | 0.82 | HKDC1 (0.34) | ALDH1A1LMNAMAPTHSD17B10KDM4E | |
| SCHEMBL17499331 | 0.81 | KMT2A (0.36) | ALDH1A1LMNAMAPTHSD17B10RAB9A | |
| SCHEMBL17499126 | 0.80 | KDM4E (0.50) | ALDH1A1LMNAMAPTKDM4ERAB9A | |
| SCHEMBL17499653 | 0.79 | ADRA2A (0.33) | ALDH1A1LMNAMAPTHSD17B10KDM4E | |
| SCHEMBL17499449 | 0.79 | HSP90AA1 (0.40) | ALDH1A1LMNAMAPTHSD17B10KDM4E | |
| SCHEMBL17499675 | 0.77 | KDM4E (0.32) | ALDH1A1LMNAMAPTHSD17B10KDM4E | |
| SCHEMBL17499293 | 0.77 | GRM5 (0.37) | ALDH1A1LMNAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |