SCHEMBL17499385

SCHEMBL17499385

C[Si](C)(C)Oc1ccccc1N=CCc1ccsc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16098638 0.85 ALDH1A1 (0.43) ALDH1A1TDP1
SCHEMBL17499389 0.82 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL17499156 0.80 CYP19A1 (0.32) ALDH1A1
SCHEMBL17499280 0.78 CYP1A2 (0.35) ALDH1A1TDP1
SCHEMBL17499494 0.78
SCHEMBL17499619 0.77
SCHEMBL17499178 0.77 RAB9A (0.36) ALDH1A1TDP1
SCHEMBL17499176 0.77 RAB9A (0.36) ALDH1A1TDP1
SCHEMBL17499256 0.76 DRD2 (0.36) ALDH1A1TDP1
SCHEMBL17499379 0.75 POLB (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed