Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040289 | 0.99 | HRH1 (0.33) | KDM4EHRH1CYP2D6KCNH2HTR6 | |
| SCHEMBL17499384 | 0.91 | HRH1 (0.33) | KDM4EHRH1CYP2D6KCNH2HTR6 | |
| SCHEMBL28210117 | 0.90 | HRH1 (0.33) | KDM4EHRH1CYP2D6KCNH2HTR6 | |
| SCHEMBL16095541 | 0.87 | KDM4E (0.43) | KDM4EHRH1HTR6GAA | |
| SCHEMBL17499393 | 0.85 | PKM (0.39) | KDM4ECYP2D6 | |
| SCHEMBL16097387 | 0.85 | KDM4E (0.34) | KDM4EHRH1CYP2D6KCNH2HTR6 | |
| SCHEMBL17499266 | 0.84 | GABRA1 (0.32) | KDM4EHRH1CYP2D6KCNH2 | |
| SCHEMBL16096465 | 0.81 | KMT2A (0.33) | KDM4E | |
| SCHEMBL17499634 | 0.80 | KDM4E (0.36) | KDM4E | |
| SCHEMBL16098400 | 0.80 | KDM4E (0.40) | KDM4EHRH1CYP2D6KCNH2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |