Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499790 | 0.99 | KDM4E (0.34) | HRH1HTR6KDM4ECYP2D6KCNH2 | |
| SCHEMBL28210117 | 0.91 | HRH1 (0.33) | HRH1HTR6KDM4ECYP2D6KCNH2 | |
| SCHEMBL17499384 | 0.90 | HRH1 (0.33) | HRH1HTR6KDM4ECYP2D6KCNH2 | |
| SCHEMBL16095541 | 0.86 | KDM4E (0.43) | HRH1HTR6KDM4E | |
| SCHEMBL17499393 | 0.84 | PKM (0.39) | KDM4ECYP2D6 | |
| SCHEMBL16097387 | 0.84 | KDM4E (0.34) | HRH1HTR6KDM4ECYP2D6KCNH2 | |
| SCHEMBL17499266 | 0.83 | GABRA1 (0.32) | HRH1KDM4ECYP2D6KCNH2 | |
| SCHEMBL28040333 | 0.80 | KDM4E (0.35) | KDM4E | |
| SCHEMBL16096465 | 0.80 | KMT2A (0.33) | KDM4E | |
| SCHEMBL16098400 | 0.79 | KDM4E (0.40) | HRH1HTR6KDM4ECYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209268-B | Heterocyclic imine functionalized polymers | 株式会社普利司通 | 2018-05-04 | — | — | CN | disclosed |
| CN-105209268-A | Heterocyclic imine functionalized polymers | BRIDGESTONE CORP | 2015-12-30 | — | — | CN | disclosed |