SCHEMBL17499384

SCHEMBL17499384

Cc1ccc(N=CCc2cnccn2)c(O[SiH](C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.33
CYP2D6 P10635 1/20 0.33
KCNH2 Q12809 1/20 0.33
GAA P10253 1/20 0.32
HTR6 P50406 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28210117 0.99 HRH1 (0.33) HRH1CYP2D6KCNH2GAAHTR6
SCHEMBL17499790 0.91 KDM4E (0.34) HRH1CYP2D6KCNH2GAAHTR6
SCHEMBL28040289 0.90 HRH1 (0.33) HRH1CYP2D6KCNH2HTR6KDM4E
SCHEMBL16098400 0.87 KDM4E (0.40) HRH1CYP2D6KCNH2GAAHTR6
SCHEMBL16096607 0.86 GAA (0.33) HRH1CYP2D6KCNH2GAAHTR6
SCHEMBL17499702 0.85 PKM (0.37) CYP2D6
SCHEMBL17499266 0.84 GABRA1 (0.32) HRH1CYP2D6KCNH2KDM4E
SCHEMBL17499522 0.81
SCHEMBL17499268 0.81 ALDH1A1 (0.32) KDM4E
SCHEMBL28040309 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed