Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | COMT | P21964 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17504087 | 0.87 | SLC6A3 (0.52) | SLC6A3COMTPDE10AALDH1A1HPGD | |
| SCHEMBL21462406 | 0.83 | SLC6A3 (0.40) | SLC6A3GAA | |
| SCHEMBL21462409 | 0.83 | SLC6A3 (0.33) | SLC6A3KMT2A | |
| SCHEMBL17504094 | 0.82 | SLC6A3 (0.41) | SLC6A3COMTPDE10AALDH1A1HPGD | |
| SCHEMBL17504073 | 0.74 | SLC6A3 (0.51) | SLC6A3KMT2AALDH1A1TSHR | |
| SCHEMBL17504068 | 0.72 | SLC6A3 (0.50) | SLC6A3KMT2AALDH1A1 | |
| SCHEMBL21462390 | 0.72 | SLC6A3 (0.37) | SLC6A3 | |
| SCHEMBL18984985 | 0.71 | SLC6A3 (0.36) | SLC6A3 | |
| SCHEMBL21462740 | 0.69 | SLC6A3 (0.40) | SLC6A3COMT | |
| SCHEMBL17504058 | 0.69 | POLB (0.39) | SLC6A3KMT2APDE10AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3553053-A1 | (S)-ENANTIOMERIC FORM OF A HETEROCYCLIC COMPOUND HAVING MOTIVATION IMPROVING AND/OR REFERENCE MEMORY ENHANCING ACTIVITY | Red Bull GmbH (AT) | 2019-10-16 | — | — | EP | claimed |
| US-10221147-B2 | Heterocyclic compounds with working memory enhancing activity | RED BULL GMBH (AT) | 2019-03-05 | — | — | US | claimed |
| US-20170174642-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | COGMOTIV FLEXCO (AT) | 2017-06-22 | — | — | US | claimed |
| US-20210380545-A1 | (S)-ENANTIOMERIC FORM OF A HETEROCYCLIC COMPOUND HAVING MOTIVATION IMPROVING AND/OR REFERENCE MEMORY ENHANCING ACTIVITY | RED BULL GMBH (AT) | 2021-12-09 | — | — | US | disclosed |
| EP-3553053-A1 | (S)-ENANTIOMERIC FORM OF A HETEROCYCLIC COMPOUND HAVING MOTIVATION IMPROVING AND/OR REFERENCE MEMORY ENHANCING ACTIVITY | Red Bull GmbH (AT) | 2019-10-16 | — | — | EP | disclosed |
| US-10221147-B2 | Heterocyclic compounds with working memory enhancing activity | RED BULL GMBH (AT) | 2019-03-05 | — | — | US | disclosed |
| US-20170174642-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | COGMOTIV FLEXCO (AT) | 2017-06-22 | — | — | US | disclosed |
| WO-2016023997-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | RED BULL GMBH (AT) | 2016-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174642-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | TAAR1, ACHE, RIF1 | SLC6A3 683/4885COMT 243/4885KMT2A 375/4885 |
| US-20210380545-A1 | (S)-ENANTIOMERIC FORM OF A HETEROCYCLIC COMPOUND HAVING MOTIVATION IMPROVING AND/OR REFERENCE MEMORY ENHANCING ACTIVITY | TFEB, TAAR1, RABGGTB | SLC6A3 444/4885COMT 16/4885KMT2A 591/4885 |
| US-10221147-B2 | Heterocyclic compounds with working memory enhancing activity | TAAR1, ACHE, RIF1 | SLC6A3 683/4885COMT 243/4885KMT2A 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.