Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | NGFR | P08138 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17505170 | 0.83 | HSD17B10 (0.49) | PARP1CA12CA9ARNGFR | |
| SCHEMBL17505211 | 0.73 | AR (0.49) | PARP1CA12CA9RAD52AR | |
| SCHEMBL1771247 | 0.70 | AR (0.55) | PARP1CA12CA9ARNGFR | |
| SCHEMBL17505198 | 0.69 | PARP1 (0.44) | PARP1CA12CA9ARNGFR | |
| SCHEMBL17505187 | 0.68 | HSD17B10 (0.74) | PARP1CA12CA9ARKDM4E | |
| SCHEMBL17505203 | 0.67 | HSD17B10 (0.56) | PARP1CA12CA9ARNGFR | |
| SCHEMBL17505210 | 0.67 | ALDH1A1 (0.65) | PARP1CA12CA9NGFRKDM4E | |
| SCHEMBL8978738 | 0.65 | HPGD (0.64) | MAPTHSD17B10CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL17505141 | 0.65 | TSHR (0.47) | PARP1CA12CA9ARKDM4E | |
| SCHEMBL28208179 | 0.65 | KEAP1 (0.44) | PARP1CA12CA9ARNGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022915-A1 | 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-11 | — | — | WO | disclosed |