Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17505205 | 0.91 | LMNA (0.54) | LMNAHPGDCYP2C9KDM4EGAA | |
| SCHEMBL7074282 | 0.85 | LMNA (0.51) | LMNAHPGDCYP2C9KDM4EGAA | |
| SCHEMBL7069908 | 0.84 | LMNA (0.50) | LMNAHPGDCYP2C9KDM4EGAA | |
| SCHEMBL2056350 | 0.79 | LMNA (0.59) | LMNAHPGDCYP2C9KDM4EGAA | |
| SCHEMBL17505185 | 0.75 | CA12 (0.49) | GAAMAPTARPOLBHTR1A | |
| SCHEMBL30639791 | 0.74 | HPGD (0.68) | LMNAHPGDCYP2C9KDM4EGAA | |
| SCHEMBL20424627 | 0.74 | HPGD (0.68) | LMNAHPGDCYP2C9KDM4EGAA | |
| SCHEMBL1420703 | 0.72 | LMNA (0.62) | LMNAHPGDCYP2C9KDM4EGAA | |
| SCHEMBL23695580 | 0.72 | GPR84 (0.52) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL7290340 | 0.71 | GPR84 (0.44) | HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022915-A1 | 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-11 | — | — | WO | disclosed |