Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | DDX3X | O00571 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | BLK | P51451 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17508316 | 0.88 | RAPGEF4 (0.57) | RAPGEF4GAAMAPTKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL17508234 | 0.86 | RAPGEF4 (0.56) | RAPGEF4GAAMAPTKDM4ETDP1 | |
| SCHEMBL17527014 | 0.85 | RAPGEF4 (0.51) | RAPGEF4GAAMAPTKDM4ETDP1 | |
| SCHEMBL17527023 | 0.83 | RAPGEF4 (0.54) | RAPGEF4GAAMAPTTDP1MEN1 | |
| Hydrochloric Acid SCHEMBL17506804 | 0.82 | RAPGEF4 (0.53) | RAPGEF4GAAMAPTTDP1MEN1 | |
| SCHEMBL5082029 | 0.79 | DDX3X (0.62) | RAPGEF4GAAMAPTKDM4ETDP1 | |
| SCHEMBL17508186 | 0.79 | TDP1 (0.60) | RAPGEF4GAAMAPTKDM4ETDP1 | |
| SCHEMBL17506815 | 0.79 | TDP1 (0.47) | GAAMAPTKDM4ETDP1MEN1 | |
| SCHEMBL17506786 | 0.78 | GAA (0.59) | RAPGEF4GAAMAPTKDM4ETDP1 | |
| SCHEMBL17166901 | 0.77 | RAPGEF4 (0.53) | RAPGEF4GAAMAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020110-A1 | OXY-, THIO- AND AZO- BIS-BENZENE TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | disclosed |
| WO-2016020110-A1 | OXY-, THIO- AND AZO- BIS-BENZENE TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | disclosed |