Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | DDX3X | O00571 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | BLK | P51451 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GNG2 | P59768 | 1/20 | 0.38 |
| ▸ | GNB1 | P62873 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17508234 | 0.98 | RAPGEF4 (0.56) | RAPGEF4GAAMAPTTDP1KDM4E | |
| SCHEMBL17506802 | 0.88 | RAPGEF4 (0.56) | RAPGEF4GAAMAPTTDP1KDM4E | |
| SCHEMBL17508283 | 0.81 | RAPGEF4 (0.46) | RAPGEF4GAAMAPTTDP1KDM4E | |
| SCHEMBL17527014 | 0.80 | RAPGEF4 (0.51) | RAPGEF4GAAMAPTTDP1KDM4E | |
| SCHEMBL5082029 | 0.80 | DDX3X (0.62) | RAPGEF4GAAMAPTTDP1KDM4E | |
| SCHEMBL16588368 | 0.79 | RAPGEF4 (0.54) | RAPGEF4GAAMAPTTDP1KDM4E | |
| SCHEMBL17166901 | 0.78 | RAPGEF4 (0.53) | RAPGEF4GAAMAPTTDP1KDM4E | |
| SCHEMBL17508186 | 0.76 | TDP1 (0.60) | RAPGEF4GAAMAPTTDP1KDM4E | |
| SCHEMBL2127990 | 0.76 | MAPT (0.86) | RAPGEF4GAAMAPTTDP1KDM4E | |
| SCHEMBL7389020 | 0.76 | MAPT (0.67) | RAPGEF4GAAMAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020112-A1 | OXIDATION DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | claimed |
| WO-2016020112-A1 | OXIDATION DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | disclosed |
| WO-2016020112-A1 | OXIDATION DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | disclosed |