Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24181290 | 0.85 | L3MBTL1 (0.46) | KIF11NR3C1ALDH1A1L3MBTL1TTR | |
| SCHEMBL756589 | 0.84 | SLC6A4 (0.43) | KIF11NR3C1ALDH1A1TTRKDM4E | |
| SCHEMBL2314319 | 0.83 | ALDH1A1 (0.49) | KIF11ARALDH1A1L3MBTL1TTR | |
| SCHEMBL6142763 | 0.81 | HSPB1 (0.58) | ARALDH1A1L3MBTL1TTRHSPB1 | |
| SCHEMBL29452473 | 0.81 | APP (0.44) | KIF11ALDH1A1TTRKMT2AKDM4E | |
| SCHEMBL3903338 | 0.80 | TTR (0.59) | KIF11ALDH1A1L3MBTL1TTRKMT2A | |
| SCHEMBL11207026 | 0.80 | AR (0.47) | KIF11ARHSPB1KMT2AMRGPRX4 | |
| SCHEMBL14662479 | 0.79 | KIF11 (0.43) | KIF11ARALDH1A1L3MBTL1TTR | |
| SCHEMBL28569057 | 0.79 | HTR2A (0.50) | ARNR3C1NR3C2MRGPRX4 | |
| SCHEMBL24512750 | 0.79 | KIF11 (0.42) | KIF11ARALDH1A1L3MBTL1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016019588-A1 | OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE | THE BROAD INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |
| WO-2016019588-A1 | OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE | THE BROAD INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |