Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17508331 | 0.86 | TDP1 (0.44) | TSHRTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL17508307 | 0.86 | MEN1 (0.46) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL17508288 | 0.81 | TDP1 (0.59) | TSHRTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL17508304 | 0.78 | ALDH1A1 (0.44) | TSHRTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL13548441 | 0.75 | TDP1 (0.58) | TSHRTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL30726456 | 0.75 | TDP1 (0.58) | TSHRTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL27438417 | 0.74 | ALDH1A1 (0.51) | TSHRTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL12287011 | 0.73 | TDP1 (0.60) | TSHRTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL17508290 | 0.72 | GSK3B (0.49) | TSHRTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL31365116 | 0.72 | TSHR (0.71) | TSHRTDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020112-A1 | OXIDATION DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | claimed |
| WO-2016020112-A1 | OXIDATION DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | disclosed |