Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17508202 | 0.86 | TSHR (0.50) | TDP1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL17508290 | 0.82 | GSK3B (0.49) | TDP1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL17508300 | 0.79 | ALDH1A1 (0.53) | TDP1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL17508307 | 0.78 | MEN1 (0.46) | TSHRMEN1KMT2AMAPK1GPR35 | |
| SCHEMBL13214336 | 0.73 | TDP1 (0.58) | TDP1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL30726456 | 0.73 | TDP1 (0.58) | TDP1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL13548441 | 0.73 | TDP1 (0.58) | TDP1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL17508288 | 0.73 | TDP1 (0.59) | TDP1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL2169225 | 0.72 | TSHR (0.53) | TDP1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL2169236 | 0.72 | TSHR (0.53) | TDP1TSHRMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020112-A1 | OXIDATION DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | claimed |
| WO-2016020112-A1 | OXIDATION DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | disclosed |