Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17508290 | 0.85 | GSK3B (0.49) | TDP1TSHRMAPTMEN1KMT2A | |
| SCHEMBL17508157 | 0.85 | MAPK1 (0.49) | TDP1TSHRMAPTLMNAMEN1 | |
| SCHEMBL14040938 | 0.81 | HPGD (0.66) | TDP1MAPTLMNAMEN1KMT2A | |
| SCHEMBL17508202 | 0.81 | TSHR (0.50) | TDP1TSHRMAPTLMNAMEN1 | |
| SCHEMBL12287011 | 0.80 | TDP1 (0.60) | TDP1TSHRMAPTLMNAMEN1 | |
| SCHEMBL17508283 | 0.79 | RAPGEF4 (0.46) | TDP1TSHRMAPTLMNAMEN1 | |
| SCHEMBL11514743 | 0.78 | TDP1 (0.68) | TDP1MAPTLMNAMEN1KMT2A | |
| SCHEMBL17414842 | 0.76 | MAPT (0.67) | TDP1MAPTLMNAMEN1KMT2A | |
| SCHEMBL9984889 | 0.76 | FGFR4 (0.49) | TDP1TSHRMAPTLMNAMEN1 | |
| SCHEMBL121896 | 0.75 | TDP1 (1.00) | TDP1TSHRMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020112-A1 | OXIDATION DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | claimed |
| WO-2016020112-A1 | OXIDATION DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | disclosed |