Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17508288 | 0.85 | TDP1 (0.59) | TSHRCYP3A4MAPK1TDP1MAPT | |
| SCHEMBL17508331 | 0.82 | TDP1 (0.44) | TSHRCYP3A4MAPK1TDP1MAPT | |
| SCHEMBL11482551 | 0.78 | HPGD (0.66) | GSK3BTSHRCYP3A4TDP1MAPT | |
| SCHEMBL17508253 | 0.77 | CYP3A4 (0.62) | TSHRCYP3A4MAPK1TDP1MAPT | |
| SCHEMBL563902 | 0.77 | CYP3A4 (0.62) | TSHRCYP3A4MAPK1TDP1MAPT | |
| SCHEMBL3742310 | 0.77 | TDP1 (0.64) | TSHRCYP3A4MAPK1TDP1MAPT | |
| SCHEMBL17506821 | 0.77 | GSK3B (0.45) | GSK3BMAPK1TDP1MAPTHTT | |
| SCHEMBL17508157 | 0.77 | MAPK1 (0.49) | TSHRCYP3A4MAPK1TDP1MAPT | |
| SCHEMBL13214336 | 0.76 | TDP1 (0.58) | TSHRCYP3A4MAPK1TDP1MAPT | |
| SCHEMBL11143295 | 0.76 | MAPT (0.70) | GSK3BTSHRCYP3A4MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020112-A1 | OXIDATION DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | claimed |
| WO-2016020112-A1 | OXIDATION DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | disclosed |