Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20788508 | 0.85 | MAPT (0.56) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL29622134 | 0.83 | ALDH1A1 (0.64) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL24928 | 0.83 | ALDH1A1 (0.64) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL5857819 | 0.81 | PDE7A (0.55) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL11715342 | 0.81 | MAPT (0.56) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL29577003 | 0.80 | TSHR (0.56) | TSHRMAPK1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL213758 | 0.80 | TSHR (0.56) | TSHRMAPK1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL68980 | 0.78 | GPR35 (0.67) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL121896 | 0.78 | TDP1 (1.00) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL3973537 | 0.78 | MAPT (0.69) | TDP1TSHRMAPK1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820302-A | Ratio type nitric oxide response near infrared fluorescent molecular probe and preparation method and application thereof | 中国药科大学 | 2024-04-05 | — | — | CN | claimed |
| EP-0659399-B1 | Process of direct hair using steam | OREAL (FR) | 1997-03-19 | — | — | EP | claimed |
| US-5496377-A | HAIR DYES, NITRO-AMINE COMPOUNDS | L'OREAL (FR) | 1996-03-05 | — | — | US | claimed |
| EP-0659399-A1 | Process of direct hair using steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | claimed |
| EP-0279016-B2 | Powdered hair dye | HOYU KK (JP) | 1995-04-05 | — | — | EP | claimed |
| US-5015769-A | Hair dyes formed by reaction of an alcohol with a phenol in the presence of a strong base for etherification followed by amination | L'OREAL (FR) | 1991-05-14 | — | — | US | claimed |
| US-4740622-A | 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols | L'OREAL (FR) | 1988-04-26 | — | — | US | claimed |
| US-4323360-A | Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent | L'OREAL (FR) | 1982-04-06 | — | — | US | claimed |
| CN-120136896-A | Disubstituted benzimidazole compound and application thereof | 暨南大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-120136897-A | 2, 8-Disubstituted quinoline macrocyclic compound and application thereof | 暨南大学 | 2025-06-13 | — | — | CN | disclosed |
| US-12258355-B2 | Probes for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2025-03-25 | — | — | US | disclosed |
| CN-117820302-A | Ratio type nitric oxide response near infrared fluorescent molecular probe and preparation method and application thereof | 中国药科大学 | 2024-04-05 | — | — | CN | disclosed |
| WO-2024041609-A1 | BENZO BICYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 广州市联瑞制药有限公司 | 2024-02-29 | — | — | WO | disclosed |
| CN-116655618-A | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| US-4419101-A | Chlorine-substituted nitro-para-phenylenediamines, a process for their preparation and their use in dyeing keratin fibres | L'OREAL (FR) | 1983-12-06 | — | — | US | disclosed |
| US-4417896-A | NITRO-,AMINO-,PHENOXYALKANOLS | SOCIETE ANONYME DITE: L'OREAL (FR) | 1983-11-29 | — | — | US | disclosed |
| US-4337061-A | NITRO DYES IN AQUEOUS SOLUTION | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-06-29 | — | — | US | disclosed |
| US-4176192-A | ANTHELMINTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-27 | — | — | US | disclosed |
| US-4068085-A | YELLOW AND RED ON POLYESTERS AND ACRYLICS | CIBA-GEIGY CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-3969526-A | Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles | SMITHKLINE CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12258355-B2 | Probes for imaging huntingtin protein | HTT, HYPK, HSPBP1 | TDP1 540/4885TSHR 3168/4885MAPK1 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.