Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | UNG | P13051 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30644949 | 0.83 | KDM4E (0.44) | ALDH1A1CYP2A6FBP1UNGNFE2L2 | |
| SCHEMBL20546680 | 0.83 | KDM4E (0.44) | ALDH1A1CYP2A6FBP1UNGNFE2L2 | |
| SCHEMBL6854130 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP2A6FBP1UNGNFE2L2 | |
| SCHEMBL29572467 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP2A6FBP1UNGNFE2L2 | |
| SCHEMBL28376764 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP2A6FBP1UNGNFE2L2 | |
| SCHEMBL6849342 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KIF11CYP2A6FBP1UNG | |
| SCHEMBL29425705 | 0.75 | FBP1 (0.56) | ALDH1A1FBP1NFE2L2MAOB | |
| SCHEMBL67201 | 0.75 | FBP1 (0.56) | ALDH1A1FBP1NFE2L2MAOB | |
| SCHEMBL6855120 | 0.73 | ALDH1A1 (0.47) | ALDH1A1CYP2A6FBP1UNGNFE2L2 | |
| SCHEMBL21699904 | 0.72 | ALDH1A1 (0.45) | ALDH1A1CYP2A6FBP1UNGNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016019588-A1 | OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE | THE BROAD INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |