SCHEMBL17514520

SCHEMBL17514520

Clc1ccc(Cl)c(COc2cc[c]cc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 3/20 0.44
MAOB P27338 1/20 0.44
ALKBH1 Q13686 1/20 0.42
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 1/20 0.39
NCOA1 Q15788 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
NR4A1 P22736 1/20 0.38
NR4A3 Q92570 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38
UBE2N P61088 1/20 0.38
PPARD Q03181 1/20 0.38
PPARA Q07869 1/20 0.38
HTR2A P28223 2/20 0.38
SLC6A4 P31645 2/20 0.38
HTR2C P28335 1/20 0.38
KCNH2 Q12809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL696921 0.86 NR4A2 (0.59) NR4A2KMT2AALDH1A1MEN1MAPT
SCHEMBL17514994 0.85 MRGPRX4 (0.43) NR4A2KMT2AMEN1HTR2ASLC6A4
SCHEMBL17514997 0.83 RAB9A (0.41) MAOBALDH1A1HTR2ASLC6A4HTR2C
SCHEMBL27650144 0.81 NR4A2 (0.41) NR4A2MAOBALKBH1ALDH1A1MAPT
SCHEMBL17514532 0.80 HPD (0.44) NR4A2MAOBKMT2AALDH1A1MEN1
SCHEMBL6331482 0.79 NR4A2 (0.48) NR4A2MAOBALKBH1KMT2AALDH1A1
SCHEMBL920476 0.79 NR4A2 (0.57) NR4A2MAOBKMT2AMEN1MAPT
SCHEMBL5512464 0.78 MAOB (0.52) NR4A2MAOBALKBH1KMT2AALDH1A1
SCHEMBL13577174 0.75 TSHR (0.52) NR4A2MAOBALKBH1KMT2AALDH1A1
SCHEMBL6235530 0.74 MAOB (0.55) NR4A2MAOBALKBH1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed