Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1304581 | 0.86 | IDO1 (0.33) | KMO | |
| SCHEMBL17514854 | 0.86 | GRM2 (0.38) | KMOGRM2EGLN2HSD11B1S100A4 | |
| SCHEMBL433432 | 0.79 | GRM2 (0.38) | KMOGRM2EGLN2HSD11B1S100A4 | |
| SCHEMBL17514578 | 0.79 | KMO (0.40) | KMOGRM2EGLN2HSD11B1S100A4 | |
| SCHEMBL433574 | 0.79 | KMO (0.35) | KMOGRM2EGLN2HSD11B1S100A4 | |
| SCHEMBL23638850 | 0.78 | S100A4 (0.46) | KMOGRM2EGLN2AHRHSD11B1 | |
| SCHEMBL30598347 | 0.78 | S100A4 (0.46) | KMOGRM2EGLN2AHRHSD11B1 | |
| SCHEMBL435281 | 0.77 | KMO (0.34) | KMOGRM2EGLN2AHRHSD11B1 | |
| SCHEMBL17514861 | 0.75 | KMO (0.35) | KMOGRM2EGLN2AHRHSD11B1 | |
| SCHEMBL17515013 | 0.75 | NISCH (0.38) | GRM2HSD11B1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016026830-A1 | NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | WO | disclosed |